Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343317 | 0.84 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL343315 | 0.84 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL343316 | 0.84 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL3712886 | 0.83 | ADORA2A (0.45) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL341583 | 0.80 | HSD17B10 (0.39) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL341581 | 0.80 | HSD17B10 (0.39) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL473587 | 0.78 | KDM4E (0.64) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL21744575 | 0.78 | KDM4E (0.66) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL10093441 | 0.77 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL10093442 | 0.77 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411011-A1 | NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION | MSD K.K. (JP) | 2012-02-01 | — | — | EP | claimed |