Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 13/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749426 | 1.00 | EED (0.42) | EEDCCNT1CDK9GRIN2BRIPK1 | |
| SCHEMBL4023587 | 0.90 | EED (0.41) | EEDCCNT1CDK9GRIN2B | |
| SCHEMBL4023583 | 0.90 | EED (0.41) | EEDCCNT1CDK9GRIN2B | |
| SCHEMBL4019575 | 0.88 | EED (0.37) | EEDCCNT1CDK9CYP2D6TAAR1 | |
| SCHEMBL4019577 | 0.88 | EED (0.37) | EEDCCNT1CDK9CYP2D6TAAR1 | |
| SCHEMBL4020952 | 0.86 | EED (0.37) | EEDCCNT1CDK9GRIN2BCYP2D6 | |
| SCHEMBL4020948 | 0.86 | EED (0.37) | EEDCCNT1CDK9GRIN2BCYP2D6 | |
| SCHEMBL4019982 | 0.86 | KMT2A (0.39) | EEDGRIN2BRIPK1 | |
| SCHEMBL4019987 | 0.86 | KMT2A (0.39) | EEDGRIN2BRIPK1 | |
| SCHEMBL4749407 | 0.85 | EED (0.32) | EEDRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |