Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531707 | 0.77 | NPC1 (0.69) | NPC1RAB9AMAPTPSMB8TP53 | |
| SCHEMBL824375 | 0.77 | NPC1 (0.69) | NPC1RAB9AMAPTPSMB8TP53 | |
| SCHEMBL10045305 | 0.76 | NPC1 (0.54) | NPC1RAB9AMAPTPSMB8TP53 | |
| SCHEMBL31590552 | 0.76 | NQO2 (0.43) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL4679272 | 0.74 | MAPT (0.61) | NPC1RAB9AMAPTPSMB8TP53 | |
| SCHEMBL30011535 | 0.73 | MAPT (0.47) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL28602639 | 0.73 | MAPT (0.47) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL5720494 | 0.73 | NPC1 (0.50) | NPC1RAB9AMAPTPSMB8TP53 | |
| SCHEMBL9542349 | 0.71 | NPC1 (0.54) | NPC1RAB9AMAPTPSMB8TP53 | |
| SCHEMBL1280187 | 0.71 | NPC1 (0.54) | NPC1RAB9AMAPTPSMB8TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213383-B | Method for catalytically synthesizing isocoumarin compounds by using ruthenium complex | 上海应用技术大学 | 2023-03-31 | — | — | CN | claimed |
| CN-113185435-B | Method for preparing beta-carbonyl sulfone compound by using half-sandwich iridium complex | 上海应用技术大学 | 2022-11-15 | — | — | CN | claimed |
| CN-113527308-B | Method for catalytic synthesis of 7-deazapurine compounds by using iron complex | 上海应用技术大学 | 2022-10-14 | — | — | CN | claimed |
| CN-112538096-B | Application of half-sandwich rhodium complex containing ortho-carboranyl benzoxazole structure | 上海应用技术大学 | 2022-08-23 | — | — | CN | claimed |
| CN-114213383-A | Method for catalytically synthesizing isocoumarin compounds by using ruthenium complex | 上海应用技术大学 | 2022-03-22 | — | — | CN | claimed |
| CN-113527308-A | Method for catalytic synthesis of 7-deazapurine compounds by using iron complex | 上海应用技术大学 | 2021-10-22 | — | — | CN | claimed |
| CN-113185435-A | Method for preparing beta-carbonyl sulfone compound by using half-sandwich iridium complex | 上海应用技术大学 | 2021-07-30 | — | — | CN | claimed |
| CN-112538096-A | Semi-sandwich rhodium complex with ortho-carborane benzoxazole structure and preparation method and application thereof | 上海应用技术大学 | 2021-03-23 | — | — | CN | claimed |
| CN-110105404-B | Ruthenium complex containing ortho-position carborane-based benzoxazole structure and preparation and application thereof | 上海应用技术大学 | 2021-02-26 | — | — | CN | claimed |
| CN-111303423-A | Polyimide substrate, manufacturing method thereof and display panel | 武汉华星光电半导体显示技术有限公司 | 2020-06-19 | — | — | CN | claimed |
| CN-110105404-A | The ruthenium complex of the benzoxazoles structure of carborane radical containing ortho position and its preparation and application | 上海应用技术大学 | 2019-08-09 | — | — | CN | claimed |
| CN-103923765-A | Detergent Composition For Process Of Manufacturing Semiconductors And Displays | COWON INNOTECH INC | 2014-07-16 | — | — | CN | claimed |
| JP-6100547-A | — | — | None | — | — | JP | disclosed |
| EP-4648853-A1 | TARGETED DEGRADATION OF VAV1 | Monte Rosa Therapeutics AG (CH) | 2025-11-19 | — | — | EP | disclosed |
| US-20250340539-A1 | IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1, AND/OR CLK4 | PERHA PHARMACEUTICALS (FR) | 2025-11-06 | — | — | US | disclosed |
| US-12391659-B2 | Benzothiazole and related compounds | SPINOGENIX, INC. (US) | 2025-08-19 | — | — | US | disclosed |
| EP-0081730-A1 | Process for the preparation of hetaryloxyacetamides | BAYER AG (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0060426-A2 | N-(2,2,2-trifluoroethyl)-N-alkyl-azolyloxyacetic-acid amides, their preparation and use as herbicides and intermediates for their preparation | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| EP-0005501-B1 | HETEROARYLOXY-ACETAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1981-11-25 | — | — | EP | disclosed |
| EP-0005501-A2 | Heteroaryloxy-acetamides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1979-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391659-B2 | Benzothiazole and related compounds | BACE1, APP, BACE2 | NPC1 1283/4885RAB9A 1512/4885MAPT 5/4885 |
| US-20250340539-A1 | IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1, AND/OR CLK4 | CLK1, CLK2, CLK3 | NPC1 4313/4885RAB9A 2151/4885MAPT 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.