Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.65 |
| ▸ | ITGAV | P06756 | 1/20 | 0.65 |
| ▸ | ITGA4 | P13612 | 17/20 | 0.60 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625223 | 1.00 | ITGB1 (0.65) | ITGB1ITGAVITGA4PTGDRITGB7 | |
| SCHEMBL4626503 | 0.83 | ITGB1 (0.76) | ITGB1ITGAVITGA4ITGB7ABL1 | |
| SCHEMBL3317055 | 0.83 | ITGB1 (0.81) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL13398404 | 0.79 | ITGB1 (0.64) | ITGB1ITGAVITGA4ITGB7ABL1 | |
| SCHEMBL4626491 | 0.79 | ITGB1 (0.73) | ITGB1ITGAVITGA4ITGB7ABL1 | |
| SCHEMBL8352229 | 0.79 | ITGB1 (1.00) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL3316398 | 0.79 | ITGB1 (1.00) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL3313373 | 0.79 | ITGB1 (1.00) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL3313356 | 0.79 | ITGB1 (1.00) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL3315439 | 0.79 | ITGB1 (0.71) | ITGB1ITGAVITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008138615-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-11-20 | — | — | WO | claimed |
| WO-2008138615-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-11-20 | — | — | WO | disclosed |