Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13705397 | 0.94 | CA1 (0.40) | TACR1RENCA1CA2CA4 | |
| SCHEMBL13705373 | 0.94 | CA1 (0.40) | TACR1RENCA1CA2CA4 | |
| SCHEMBL4283333 | 0.93 | TACR1 (0.39) | TACR1RENCA1CA2CA4 | |
| SCHEMBL8131730 | 0.88 | HCRTR1 (0.35) | RENCA1CA2CA4CA9 | |
| SCHEMBL4752679 | 0.88 | CA1 (0.42) | TACR1RENCA1CA2CA4 | |
| SCHEMBL4281927 | 0.86 | CA1 (0.41) | RENCA1CA2CA4CA9 | |
| SCHEMBL4289518 | 0.86 | CA1 (0.44) | TACR1RENCA1CA2CA4 | |
| SCHEMBL4283871 | 0.86 | CA1 (0.44) | TACR1RENCA1CA2CA4 | |
| SCHEMBL4296474 | 0.86 | CA1 (0.44) | TACR1RENCA1CA2CA4 | |
| SCHEMBL4283733 | 0.86 | CA1 (0.44) | TACR1RENCA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |