Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.73 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.73 |
| ▸ | POLA1 | P09884 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680341 | 0.91 | PDE3A (0.71) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL6679597 | 0.90 | PDE3A (0.69) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL6679596 | 0.90 | PDE3A (0.69) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL382458 | 0.90 | PDE3A (0.75) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL19758224 | 0.90 | PDE3A (0.75) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL15788426 | 0.90 | PDE3A (0.75) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL25390812 | 0.89 | PDE3A (0.68) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL16426708 | 0.89 | PDE3A (0.68) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL6680524 | 0.89 | PDE3A (0.68) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL23153089 | 0.89 | PDE3A (0.68) | PDE3APDE4DSLC29A1POLA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129530-A1 | GEMCITABINE PRODUCTION PROCESS | CHEMAGIS LTD. (IL) | 2008-10-30 | — | — | WO | claimed |
| WO-2008129530-A1 | GEMCITABINE PRODUCTION PROCESS | CHEMAGIS LTD. (IL) | 2008-10-30 | — | — | WO | disclosed |