Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4178170 | 0.96 | BDKRB1 (0.79) | BDKRB1 | |
| SCHEMBL4755598 | 0.90 | BDKRB1 (0.83) | BDKRB1 | |
| SCHEMBL4175951 | 0.87 | BDKRB1 (0.82) | BDKRB1 | |
| SCHEMBL4172997 | 0.87 | BDKRB1 (0.89) | BDKRB1 | |
| SCHEMBL4168628 | 0.85 | BDKRB1 (0.93) | BDKRB1 | |
| SCHEMBL4169688 | 0.85 | BDKRB1 (0.93) | BDKRB1 | |
| SCHEMBL3541124 | 0.85 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL3529411 | 0.85 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL3529413 | 0.85 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL4183669 | 0.84 | BDKRB1 (0.77) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963285-A1 | BRADYKININ 1 RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007067629-A1 | BRADYKININ 1 RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 2007-06-14 | — | — | WO | claimed |
| EP-1963285-A1 | BRADYKININ 1 RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007067629-A1 | BRADYKININ 1 RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 2007-06-14 | — | — | WO | disclosed |