Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 8/20 | 0.61 |
| ▸ | ITGAV | P06756 | 1/20 | 0.61 |
| ▸ | ITGA4 | P13612 | 13/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.44 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318583 | 0.81 | ITGB1 (0.59) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL3317244 | 0.81 | ITGB1 (0.70) | ITGB1ITGAVITGA4ITGB7ABL1 | |
| SCHEMBL3312810 | 0.80 | ITGB1 (0.60) | ITGB1ITGAVITGA4ITGB7ABL1 | |
| SCHEMBL3320849 | 0.78 | ITGB1 (0.56) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL4625053 | 0.78 | ITGB1 (0.56) | ITGB1ITGAVITGA4ITGB7 | |
| Bicarbonate SCHEMBL4625471 | 0.77 | ITGB1 (0.63) | ITGB1ITGAVITGA4ITGB7ABL1 | |
| Bicarbonate SCHEMBL4625273 | 0.77 | ITGB1 (0.63) | ITGB1ITGAVITGA4ITGB7ABL1 | |
| SCHEMBL6140062 | 0.77 | ITGB1 (0.59) | ITGB1ITGAVITGA4ITGB7ABL1 | |
| SCHEMBL6139884 | 0.77 | ITGB1 (0.59) | ITGB1ITGAVITGA4ITGB7ABL1 | |
| SCHEMBL3313373 | 0.76 | ITGB1 (1.00) | ITGB1ITGAVITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008125215-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-10-23 | — | — | WO | disclosed |