Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | TPH1 | P17752 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22619755 | 0.86 | HTT (0.66) | HTTCSNK1DMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL28816448 | 0.86 | HTT (0.66) | HTTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29886565 | 0.86 | HTT (0.66) | HTTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL31039805 | 0.86 | HTT (0.66) | HTTCSNK1DMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL2554648 | 0.85 | HTT (0.67) | HTTMAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL31591599 | 0.82 | HTT (0.71) | HTTCSNK1DMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL31591590 | 0.80 | HTT (0.64) | HTTMAPTMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL3233714 | 0.80 | HTT (0.71) | HTTMAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL28816290 | 0.80 | HTT (0.71) | HTTMAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL29886352 | 0.80 | HTT (0.71) | HTTMAPTMAPK1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129129-A1 | HETEROCYCLIC PHENYL CARBAMATES AS NOVEL FAAH-INHIBITORS | KUOPION YLIOPISTO (FI) | 2008-10-30 | — | — | WO | disclosed |
| WO-2008129129-A1 | HETEROCYCLIC PHENYL CARBAMATES AS NOVEL FAAH-INHIBITORS | KUOPION YLIOPISTO (FI) | 2008-10-30 | — | — | WO | disclosed |