Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.55 |
| ▸ | FNTA | P49354 | 5/20 | 0.50 |
| ▸ | FNTB | P49356 | 3/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | ICMT | O60725 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13142541 | 0.93 | TRPV1 (0.61) | TRPV1FNTAFNTBPGGT1BTRPA1 | |
| SCHEMBL3080773 | 0.93 | TRPV1 (0.61) | TRPV1FNTAFNTBPGGT1BTRPA1 | |
| SCHEMBL13142540 | 0.88 | TRPV1 (0.56) | TRPV1FNTAFNTBPGGT1BTRPA1 | |
| SCHEMBL3082365 | 0.88 | TRPV1 (0.56) | TRPV1FNTAFNTBPGGT1BTRPA1 | |
| SCHEMBL17007389 | 0.85 | TRPV1 (0.55) | TRPV1FNTAFNTBPGGT1BTRPA1 | |
| SCHEMBL318354 | 0.85 | TRPV1 (0.55) | TRPV1FNTAFNTBPGGT1BTRPA1 | |
| SCHEMBL794999 | 0.84 | TRPV1 (0.57) | TRPV1FNTAFNTBPGGT1BTRPA1 | |
| SCHEMBL807718 | 0.84 | TRPV1 (0.57) | TRPV1FNTAFNTBPGGT1BTRPA1 | |
| SCHEMBL794998 | 0.84 | TRPV1 (0.57) | TRPV1FNTAFNTBPGGT1BTRPA1 | |
| SCHEMBL10873215 | 0.81 | TRPV1 (0.64) | TRPV1FNTAFNTBPGGT1BTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008143947-A1 | FARNESYLAMINE DERIVATIVES AND METHODS OF USE | UNIVERSITY OF SOUTH FLORIDA (US) | 2008-11-27 | — | — | WO | disclosed |