⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589143 | 0.88 | — | — | |
| SCHEMBL25424577 | 0.82 | — | — | |
| SCHEMBL21396234 | 0.76 | — | — | |
| SCHEMBL8768904 | 0.76 | — | — | |
| SCHEMBL14088996 | 0.76 | — | — | |
| SCHEMBL1366339 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL10937460 | 0.73 | — | — | |
| SCHEMBL22142804 | 0.71 | — | — | |
| SCHEMBL1387493 | 0.71 | — | — | |
| SCHEMBL7368734 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046235-A9 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2012-02-23 | — | — | US | claimed |
| EP-1933878-B1 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DE GMBH (DE) | 2012-02-01 | — | — | EP | claimed |
| EP-2279752-A2 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | Fresenius Kabi Deutschland GmbH (DE) | 2011-02-02 | — | — | EP | claimed |
| US-20100311670-A1 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-09 | — | — | US | claimed |
| US-20080207562-A1 | Conjugates of Hydroxyalkyl Starch and Active Substance, Prepared by Chemical Ligation Via Thiazolidine | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2008-08-28 | — | — | US | claimed |
| EP-1933878-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | Fresenius Kabi Deutschland GmbH (DE) | 2008-06-25 | — | — | EP | claimed |
| WO-2007031266-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2007-03-22 | — | — | WO | claimed |
| EP-1762250-A1 | Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine | Fresenius Kabi Deutschland GmbH (DE) | 2007-03-14 | — | — | EP | claimed |
| EP-1732609-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND A PROTEIN | Fresenius Kabi Deutschland GmbH (DE) | 2006-12-20 | — | — | EP | claimed |
| WO-2005092391-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND A PROTEIN | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2005-10-06 | — | — | WO | claimed |
| US-20240300997-A1 | PROTEIN FOLDING AGENT | TOHOKU UNIVERSITY (JP) | 2024-09-12 | — | — | US | disclosed |
| EP-4303224-A1 | PROTEIN FOLDING AGENT | Tohoku University (JP) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022186243-A1 | PROTEIN FOLDING AGENT | 国立大学法人東北大学 | 2022-09-09 | — | — | WO | disclosed |
| US-20120046235-A9 | Conjugates of hydroxyalkyl starch and a protein, prepared by native chemical ligation | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-1933878-B1 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DE GMBH (DE) | 2012-02-01 | — | — | EP | disclosed |
| EP-1933878-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | Fresenius Kabi Deutschland GmbH (DE) | 2008-06-25 | — | — | EP | disclosed |
| US-20080076700-A1 | Method for the Preparation of Oxime, Thiazolidine, Dithiane, Dithiolane, or Hydrazone Linked Analogues of Growth Hormone | NOVO NORDISK A/S (DK) | 2008-03-27 | — | — | US | disclosed |
| US-20080076700-A1 | Method for the Preparation of Oxime, Thiazolidine, Dithiane, Dithiolane, or Hydrazone Linked Analogues of Growth Hormone | NOVO NORDISK A/S (DK) | 2008-03-27 | — | — | US | disclosed |
| WO-2007031266-A2 | CONJUGATES OF HYDROXYALKYL STARCH AND AN ACTIVE SUBSTANCE, PREPARED BY CHEMICAL LIGATION VIA THIAZOLIDINE | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2007-03-22 | — | — | WO | disclosed |
| EP-1762250-A1 | Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine | Fresenius Kabi Deutschland GmbH (DE) | 2007-03-14 | — | — | EP | disclosed |