Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 16/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019756 | 0.89 | GRIN2B (0.40) | GRIN2BGRIN1MEN1KMT2AMAPK1 | |
| SCHEMBL4019761 | 0.89 | GRIN2B (0.40) | GRIN2BGRIN1MEN1KMT2AMAPK1 | |
| SCHEMBL4027216 | 0.87 | KMT2A (0.41) | GRIN2BGRIN1MEN1KMT2AMAPK1 | |
| SCHEMBL4019982 | 0.83 | KMT2A (0.39) | GRIN2BMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL4019987 | 0.83 | KMT2A (0.39) | GRIN2BMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL4021213 | 0.81 | GRIN2B (0.38) | GRIN2BMEN1KMT2AALDH1A1 | |
| SCHEMBL4022415 | 0.81 | GRIN2B (0.38) | GRIN2BMEN1KMT2AALDH1A1 | |
| SCHEMBL4021208 | 0.81 | GRIN2B (0.38) | GRIN2BMEN1KMT2AALDH1A1 | |
| SCHEMBL4751821 | 0.80 | MEN1 (0.36) | GRIN2BGRIN1MEN1KMT2AMAPK1 | |
| SCHEMBL4019759 | 0.80 | MEN1 (0.37) | GRIN2BGRIN1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |