Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | BCL9 | O00512 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14307582 | 1.00 | GAA (0.58) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL4683792 | 0.88 | GAA (0.60) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL9237410 | 0.86 | GAA (0.57) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL9299508 | 0.86 | GAA (0.57) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL9435291 | 0.85 | GAA (0.57) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL31627961 | 0.85 | GAA (0.57) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL515913 | 0.85 | GAA (0.57) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL16922669 | 0.85 | GAA (0.57) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL18285287 | 0.85 | GAA (0.57) | GAABCL9CTNNB1HTR2ASMN1; SMN2 | |
| SCHEMBL16671852 | 0.85 | GAA (0.57) | GAABCL9CTNNB1HTR2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1509334-B | Transformant producing PF1022 substance derivatives, process for producing same and novel/biosynthesis gene | MEIJI SEIKA KAISHA | 2010-04-28 | — | — | CN | disclosed |
| JP-2008092952-A | METHOD FOR PREPARATION OF SUBSTITUTED ARYL LACTIC ACID CONTAINING CYCLODEPSIPEPTIDES WITH 24 RING ATOMS | BAYER AG | 2008-04-24 | — | — | JP | disclosed |
| CN-1509334-A | Transformant producing PF1022 substance derivatives, process for producing same and novel/biosynthesis gene | �����Ƹ���ʽ���� | 2004-06-30 | — | — | CN | disclosed |
| CN-1113101-C | Process for the preparation of substituted aryl lactic acid containing cyclodepsipeptides with 24 ring atoms | BAYER AG (DE) | 2003-07-02 | — | — | CN | disclosed |
| CN-1082052-C | process for preparing cyclic depsipeptide compounds and novel cyclic depsipeptides | MEIJI SEIKA KAISHA (JP) | 2002-04-03 | — | — | CN | disclosed |
| CN-1230182-A | Process for producing cyclodepsipeptide compounds and novel cyclodepsipeptide | MEIJI SEIKA KAISHA (JP) | 1999-09-29 | — | — | CN | disclosed |
| CN-1208439-A | Process for the preparation of substituted aryl lactic acid containing cyclodepsipeptides with 24 ring atoms | BAYER AG (DE) | 1999-02-17 | — | — | CN | disclosed |