Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753012 | 0.88 | KMT2A (0.63) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4958305 | 0.84 | NPC1 (0.65) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13789666 | 0.81 | KMT2A (0.63) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7930548 | 0.81 | KMT2A (0.63) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5296521 | 0.81 | NPC1 (0.77) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11578842 | 0.79 | KMT2A (0.69) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31469807 | 0.79 | KDM4E (0.61) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13040501 | 0.79 | KMT2A (0.60) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5063495 | 0.79 | KMT2A (0.64) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4749278 | 0.78 | NPC1 (0.55) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | disclosed |