Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 16/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4293040 | 1.00 | HCRTR2 (0.43) | HCRTR2HCRTR1CHEK2 | |
| SCHEMBL4290656 | 0.93 | HCRTR2 (0.40) | HCRTR2HCRTR1CHEK2 | |
| SCHEMBL4292999 | 0.92 | HCRTR1 (0.45) | HCRTR2HCRTR1CHEK2 | |
| SCHEMBL4291088 | 0.92 | HCRTR2 (0.40) | HCRTR2HCRTR1CHEK2 | |
| SCHEMBL13705478 | 0.90 | HCRTR1 (0.44) | HCRTR2HCRTR1CHEK2 | |
| SCHEMBL13705475 | 0.88 | HCRTR1 (0.42) | HCRTR2HCRTR1CHEK2 | |
| SCHEMBL13819440 | 0.88 | HCRTR1 (0.42) | HCRTR2HCRTR1CHEK2 | |
| SCHEMBL4293415 | 0.88 | HCRTR1 (0.44) | HCRTR2HCRTR1CHEK2 | |
| SCHEMBL13705472 | 0.86 | HCRTR1 (0.41) | HCRTR2HCRTR1CHEK2 | |
| SCHEMBL4281285 | 0.86 | HCRTR1 (0.43) | HCRTR2HCRTR1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |