Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.65 |
| ▸ | KLK7 | P49862 | 11/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 8/20 | 0.52 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21574397 | 1.00 | BCHE (0.65) | BCHEKLK7KLK5PSEN1PSEN2 | |
| SCHEMBL17104794 | 0.92 | BCHE (0.58) | BCHEKLK7KLK5PSEN1PSEN2 | |
| SCHEMBL12258542 | 0.90 | BCHE (0.60) | BCHEKLK7KLK5 | |
| SCHEMBL12258553 | 0.90 | BCHE (0.56) | BCHEKLK7KLK5 | |
| SCHEMBL12902908 | 0.90 | BCHE (0.60) | BCHEKLK7KLK5 | |
| SCHEMBL21258139 | 0.90 | BCHE (0.60) | BCHEKLK7KLK5 | |
| SCHEMBL2392192 | 0.90 | BCHE (0.60) | BCHEKLK7KLK5 | |
| SCHEMBL21096773 | 0.90 | BCHE (0.56) | BCHEKLK7KLK5 | |
| SCHEMBL16403009 | 0.90 | BCHE (0.60) | BCHEKLK7KLK5 | |
| SCHEMBL2399000 | 0.90 | BCHE (0.60) | BCHEKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147472-A1 | ETHERS OF BISANHYDROHEXITOLS | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2008-12-04 | — | — | WO | disclosed |
| US-20080021209-A1 | Ethers of bisanhydrohexitols | NEW JERSEY INSTITUTE OF TECHNOLOGY (US) | 2008-01-24 | — | — | US | disclosed |
| US-20070282042-A1 | Esters of anhydrosugar alcohols as plasticizers | UNITED STATE DEPARTMENT OF ENERGY | 2007-12-06 | — | — | US | disclosed |
| US-4169152-A | Isohexide and tetrahydrofuran ethers and their carbamates in method of bringing about relaxation of skeletal musculature | ICI AMERICAS INC. (US) | 1979-09-25 | — | — | US | disclosed |