Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 12/20 | 0.45 |
| ▸ | DKK1 | O94907 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20361212 | 0.88 | MAPT (0.46) | PANK3PDE10ADKK1 | |
| SCHEMBL20367372 | 0.85 | PANK3 (0.45) | PANK3DKK1 | |
| SCHEMBL31402773 | 0.83 | SMO (0.50) | PANK3DKK1 | |
| SCHEMBL31402771 | 0.83 | SMO (0.50) | PANK3DKK1 | |
| SCHEMBL11321905 | 0.80 | TSHR (0.58) | — | |
| SCHEMBL460460 | 0.79 | KDM4E (0.56) | MAPK8MAPK10PDE10AHIF1A | |
| SCHEMBL14788209 | 0.78 | MAPK8 (0.46) | MAPK8MAPK10PDE10A | |
| SCHEMBL10491619 | 0.77 | PANK3 (0.38) | PANK3PDE10ADKK1 | |
| SCHEMBL31402759 | 0.77 | SMO (0.42) | PANK3PDE10A | |
| SCHEMBL31402767 | 0.77 | SMO (0.42) | PANK3PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140421-A2 | HETEROCYCLOALKYL SUBSTITUTED PYRIMIDINE DERIVATIVES | S*BIO PTE LTD (SG) | 2008-11-20 | — | — | WO | disclosed |