Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 5/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4290076 | 1.00 | CA1 (0.43) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL4292773 | 0.94 | DPP4 (0.43) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL13705355 | 0.93 | CA1 (0.40) | CA1CA2CA4CA9DPP4 | |
| Hydrochloric Acid SCHEMBL4286645 | 0.93 | CA1 (0.39) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL4292421 | 0.93 | CA1 (0.44) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL4295394 | 0.92 | CA1 (0.47) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL4281941 | 0.92 | CA1 (0.47) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL4293971 | 0.92 | CA1 (0.47) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL4292390 | 0.92 | CA1 (0.47) | CA1CA2CA4CA9DPP4 | |
| SCHEMBL13705359 | 0.91 | CA1 (0.46) | CA1CA2CA4CA9DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |