Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | CCKAR | P32238 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752441 | 0.94 | CA1 (0.36) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL4752935 | 0.93 | CA1 (0.43) | CA1CA2CA4CA9ROCK1 | |
| SCHEMBL13705205 | 0.91 | CA1 (0.41) | CA1CA2CA4CA9L3MBTL1 | |
| SCHEMBL4752660 | 0.90 | CA1 (0.40) | CA1CA2CA4CA9ROCK1 | |
| SCHEMBL4293386 | 0.89 | CA1 (0.45) | CA1CA2CA4CA9ROCK1 | |
| SCHEMBL13705208 | 0.89 | CA1 (0.41) | CA1CA2CA4CA9L3MBTL1 | |
| SCHEMBL13705207 | 0.89 | CA1 (0.39) | CA1CA2CA4CA9L3MBTL1 | |
| SCHEMBL13705206 | 0.89 | CA1 (0.39) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL13705288 | 0.86 | CA1 (0.38) | CA1CA2CA4CA9ROCK1 | |
| SCHEMBL13705173 | 0.85 | CA1 (0.36) | CA1CA2CA4CA9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |