Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26095675 | 0.89 | AR (0.70) | AR | |
| SCHEMBL30104279 | 0.81 | AR (1.00) | AR | |
| SCHEMBL13872000 | 0.81 | AR (1.00) | AR | |
| SCHEMBL13481661 | 0.81 | AR (1.00) | AR | |
| SCHEMBL3181633 | 0.81 | AR (1.00) | AR | |
| SCHEMBL23844286 | 0.81 | AR (1.00) | AR | |
| SCHEMBL3183275 | 0.81 | AR (1.00) | AR | |
| SCHEMBL26448217 | 0.80 | AR (0.57) | AR | |
| SCHEMBL7178500 | 0.79 | AR (0.47) | AR | |
| SCHEMBL14075769 | 0.77 | AR (0.77) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157291-A2 | CRYSTALLINE FORMS OF (3Aα, 4β, 5α, 7β, 7Aα)-4-(OCTAHYDRO-5-ETHYLSULFONAMIDO-4,7-DIMETHYL-1,3-DIOXO-4,7-EPOXY-2H-ISOINDOL-2-YL)-2-(TRIFLUOROMETHYL)BENZONITRILE AND METHOD OF PREPARATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-24 | — | — | WO | disclosed |