Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4788366 | 0.79 | GAA (0.78) | GAAMEN1KMT2AHSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL4907796 | 0.79 | GAA (0.56) | GAADRD4HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL4752998 | 0.78 | — | — | |
| SCHEMBL4753181 | 0.69 | POLB (0.44) | ALDH1A1 | |
| SCHEMBL5781658 | 0.66 | KMT2A (0.36) | MEN1KMT2ATSHRHTR2AALDH1A1 | |
| SCHEMBL18948505 | 0.65 | KDM4E (0.55) | MEN1KMT2AHSD17B10KDM4ENPSR1 | |
| SCHEMBL18948479 | 0.64 | KDM4E (0.54) | MEN1KMT2AHSD17B10TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL4788651 | 0.64 | GAA (0.57) | GAAMEN1KMT2ATSHRKDM4E | |
| SCHEMBL2328393 | 0.62 | KMT2A (0.39) | KMT2AKDM4EHTR2AALDH1A1 | |
| SCHEMBL4750793 | 0.62 | NPC1 (0.36) | MEN1KMT2ATSHRHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |