⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16193885 | 1.00 | — | — | |
| SCHEMBL3313853 | 0.82 | — | — | |
| SCHEMBL19387688 | 0.82 | — | — | |
| SCHEMBL17996881 | 0.76 | — | — | |
| SCHEMBL19387693 | 0.76 | — | — | |
| SCHEMBL195184 | 0.76 | — | — | |
| SCHEMBL3317704 | 0.76 | — | — | |
| SCHEMBL19387696 | 0.76 | — | — | |
| SCHEMBL13448666 | 0.76 | — | — | |
| SCHEMBL37806 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3178 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11958861-B2 | Spirocyclic lactams as JAK2 V617F inhibitors | INCYTE CORPORATION (US) | 2024-04-16 | — | — | US | claimed |
| CN-117843566-A | Polysubstituted benzene derivative, composition and use thereof | 康迈迪森(北京)医药科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| EP-4333822-A1 | COMPOSITION COMPRISING AN INHIBITOR OF MITOCHONDRIAL TRANSCRIPTION | Lead Discovery Center GmbH (DE) | 2024-03-13 | — | — | EP | claimed |
| EP-4298099-A1 | SPIROCYCLIC LACTAMS AS JAK2 V617F INHIBITORS | Incyte Corporation (US) | 2024-01-03 | — | — | EP | claimed |
| CN-117279966-A | Epoxy resin modifier, epoxy resin composition containing the same, adhesive comprising the epoxy resin composition, and resin cured product obtained by curing the epoxy resin composition | 大塚化学株式会社 | 2023-12-22 | — | — | CN | claimed |
| US-20230286965-A1 | BICYCLIC COMPOUND AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2023-09-14 | — | — | US | claimed |
| EP-3388433-B1 | PHTHALAZINE DERIVATIVES, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI SIMR BIOTECH CO LTD (CN) | 2023-08-30 | — | — | EP | claimed |
| US-20230219913-A1 | Sulfamoylamide Derivatives | HOFFMANN-LA ROCHE INC. (US) | 2023-07-13 | — | — | US | claimed |
| WO-2023064368-A1 | NOVEL RHODANINE DERIVATIVES AND USES THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-04-20 | — | — | WO | claimed |
| WO-2023064152-A1 | TRICYCLIC SULFAMIDES AND SULTAMS | MERCK SHARP & DOHME LLC (US) | 2023-04-20 | — | — | WO | claimed |
| US-6143747-A | ENZYME INHIBITORS | G. D. SEARLE & CO. (US) | 2000-11-07 | — | — | US | claimed |
| EP-1000055-A1 | SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS | G.D. Searle & Co. (US) | 2000-05-17 | — | — | EP | claimed |
| WO-1999065897-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 1999-12-23 | — | — | WO | claimed |
| US-5985872-A | THERAPEUTIC TREATMENT OF HERPES VIRAL INFECTION | G.D. SEARLE & CO. (US) | 1999-11-16 | — | — | US | claimed |
| WO-1999051605-A1 | PYRROLO[1,2-a]PYRAZINE sPLA2 INHIBITOR | SHIONOGI & CO., LTD. (JP) | 1999-10-14 | — | — | WO | claimed |
| WO-1998052940-A1 | SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS | G.D. SEARLE AND CO. (US) | 1998-11-26 | — | — | WO | claimed |
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | claimed |
| EP-0804428-A1 | BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-11-05 | — | — | EP | claimed |
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | claimed |
| WO-1996022287-A1 | BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-07-25 | — | — | WO | claimed |