⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894450 | 1.00 | — | — | |
| SCHEMBL1353529 | 1.00 | — | — | |
| SCHEMBL62366 | 1.00 | — | — | |
| SCHEMBL1353528 | 1.00 | — | — | |
| SCHEMBL1492517 | 1.00 | — | — | |
| SCHEMBL3106879 | 0.96 | — | — | |
| SCHEMBL9413778 | 0.96 | — | — | |
| SCHEMBL28726884 | 0.96 | — | — | |
| SCHEMBL15484260 | 0.96 | TSHR (0.53) | — | |
| SCHEMBL20895863 | 0.93 | TSHR (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708319-B2 | Biphenyl amides with modified ether groups as HSP90 inhibitors and HSP70 inducers | UNIVERSITY OF KANSAS (US) | 2023-07-25 | — | — | US | disclosed |
| US-10577373-B2 | TYK2 inhibitors and uses thereof | Nimbus Lakshimi, Inc. (US) | 2020-03-03 | — | — | US | disclosed |
| WO-2019173293-A1 | AFFINITY PURIFICATION OF GLYCOSIDE-CLEAVING ENZYMES | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2019-09-12 | — | — | WO | disclosed |
| US-20190256519-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-08-22 | — | — | US | disclosed |
| US-20180057446-A1 | BIPHENYL AMIDES WITH MODIFIED ETHER GROUPS AS HSP90 INHIBITORS AND HSP70 INDUCERS | REATA PHARMACEUTICALS, INC. | 2018-03-01 | — | — | US | disclosed |
| EP-2048168-A2 | Process for producing catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | Sumitomo Chemical Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-1966218-A1 | NOVEL, CYCLIC SUBSTITUTED FUROPYRIMIDINE DERIVATIVES AND USE THEREOF FOR TREATING CARDIOVASCULAR DISEASES | Bayer HealthCare AG (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007079861-A1 | NOVEL, CYCLIC SUBSTITUTED FUROPYRIMIDINE DERIVATIVES AND USE THEREOF FOR TREATING CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |