Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 7/20 | 0.38 |
| ▸ | DRD4 | P21917 | 7/20 | 0.38 |
| ▸ | DRD3 | P35462 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4291124 | 0.77 | CYP2D6 (0.37) | ADRA2CADRA1DHRH1SLC6A3TMEM97 | |
| SCHEMBL3493839 | 0.74 | EGFR (0.48) | DRD2DRD4DRD3KDM4EMEN1 | |
| SCHEMBL3494237 | 0.73 | DRD4 (0.48) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL4294331 | 0.71 | CA1 (0.48) | SLC6A3 | |
| SCHEMBL4281780 | 0.70 | CA1 (0.42) | — | |
| SCHEMBL4293107 | 0.70 | CA1 (0.48) | SLC6A3 | |
| SCHEMBL4293038 | 0.70 | CA1 (0.48) | SLC6A3 | |
| SCHEMBL3495249 | 0.70 | JAK2 (0.46) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL3491368 | 0.70 | JAK2 (0.46) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL3493634 | 0.70 | JAK2 (0.46) | DRD2DRD4DRD3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |