Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753760 | 1.00 | CA1 (0.42) | CA1CA2TDP1SMN1; SMN2CHRM1 | |
| SCHEMBL15015843 | 1.00 | CA1 (0.42) | CA1CA2TDP1SMN1; SMN2CHRM1 | |
| SCHEMBL16626822 | 0.90 | CA1 (0.48) | CA1CA2SMN1; SMN2ZDHHC7KMT2A | |
| SCHEMBL14601911 | 0.90 | CA1 (0.48) | CA1CA2SMN1; SMN2ZDHHC7KMT2A | |
| SCHEMBL11534552 | 0.83 | TDP1 (0.39) | CA2TDP1CHRM1AKR1A1CHRM3 | |
| SCHEMBL28810487 | 0.82 | CA1 (0.34) | CA1CA2SMN1; SMN2KMT2AMME | |
| SCHEMBL27951378 | 0.82 | CA1 (0.34) | CA1CA2SMN1; SMN2KMT2AMME | |
| SCHEMBL28810486 | 0.82 | CA1 (0.34) | CA1CA2SMN1; SMN2KMT2AMME | |
| SCHEMBL4426492 | 0.82 | CA1 (0.39) | CA1CA2TDP1SMN1; SMN2CHRM1 | |
| SCHEMBL13761133 | 0.82 | TDP1 (0.50) | CA2TDP1CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | disclosed |