Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753762 | 1.00 | CYP1A2 (0.47) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL5458824 | 0.85 | CYP1A2 (0.50) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL5436488 | 0.85 | CYP1A2 (0.50) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL5448092 | 0.85 | CYP1A2 (0.50) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL5441719 | 0.85 | CYP1A2 (0.50) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL4755975 | 0.85 | CYP1A2 (0.50) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL5453346 | 0.85 | CYP1A2 (0.50) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL4755970 | 0.85 | CYP1A2 (0.50) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL5447752 | 0.79 | CYP1A2 (0.44) | CYP1A2USP2ALDH1A1LMNATSHR | |
| SCHEMBL5436131 | 0.79 | CYP1A2 (0.44) | CYP1A2USP2ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | disclosed |