Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 19/20 | 0.56 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099328 | 0.96 | PRKCQ (0.56) | PRKCQ | |
| SCHEMBL13999405 | 0.96 | PRKCQ (0.56) | PRKCQ | |
| SCHEMBL5102644 | 0.94 | PRKCQ (0.55) | PRKCQ | |
| SCHEMBL13999401 | 0.94 | PRKCQ (0.55) | PRKCQ | |
| SCHEMBL5095837 | 0.91 | PRKCQ (0.59) | PRKCQ | |
| SCHEMBL13999408 | 0.91 | PRKCQ (0.59) | PRKCQ | |
| SCHEMBL5099323 | 0.88 | PRKCQ (0.52) | PRKCQ | |
| SCHEMBL4697486 | 0.86 | PRKCQ (0.59) | PRKCQ | |
| SCHEMBL4697483 | 0.86 | PRKCQ (0.59) | PRKCQ | |
| SCHEMBL5102647 | 0.86 | PRKCQ (0.54) | PRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966163-A1 | PYRIMIDINE DERIVATIVES USEFUL AS INHIBITORS OF PKC-THETA | Boehringer Ingelheim International GmbH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007076247-A1 | PYRIMIDINE DERIVATIVES USEFUL AS INHIBITORS OF PKC-THETA | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-07-05 | — | — | WO | disclosed |