Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 16/20 | 0.95 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.95 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129509 | 0.98 | GRIA2 (1.00) | GRIA2CYP2D6CYP2C9CYP1A2GAA | |
| SCHEMBL3139195 | 0.96 | GRIA2 (0.98) | GRIA2CYP2D6CYP2C9CYP1A2GAA | |
| SCHEMBL3127012 | 0.95 | GRIA2 (0.95) | GRIA2CYP2D6CYP2C9CYP1A2GAA | |
| SCHEMBL3136897 | 0.89 | GRIA2 (0.83) | GRIA2CYP2D6CYP2C9CYP1A2GAA | |
| SCHEMBL4753759 | 0.86 | GRIA2 (0.76) | GRIA2CYP2D6CYP2C9CYP1A2GAA | |
| SCHEMBL1423841 | 0.85 | GRIA2 (0.74) | GRIA2CYP2D6CYP2C9CYP1A2GAA | |
| SCHEMBL1423822 | 0.85 | GRIA2 (0.74) | GRIA2CYP2D6CYP2C9CYP1A2GAA | |
| SCHEMBL1423867 | 0.85 | GRIA2 (1.00) | GRIA2CYP2D6CYP2C9CYP1A2GAA | |
| SCHEMBL1423653 | 0.85 | GRIA2 (0.84) | GRIA2CYP2D6CYP2C9CYP1A2GAA | |
| SCHEMBL3143259 | 0.85 | GRIA2 (0.78) | GRIA2CYP2D6CYP2C9CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008148832-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEROF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | claimed |
| WO-2008148832-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEROF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |