Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530373 | 1.00 | CALCRL (0.65) | CALCRLKCNH2 | |
| SCHEMBL12219862 | 0.90 | CALCRL (0.67) | CALCRLKCNH2 | |
| SCHEMBL12219810 | 0.88 | CALCRL (0.69) | CALCRLKCNH2 | |
| SCHEMBL12219859 | 0.86 | CALCRL (0.68) | CALCRL | |
| SCHEMBL12219849 | 0.85 | CALCRL (0.49) | CALCRLKCNH2 | |
| SCHEMBL2528652 | 0.85 | CALCRL (0.66) | CALCRLKCNH2 | |
| SCHEMBL12219863 | 0.84 | CALCRL (0.65) | CALCRL | |
| SCHEMBL12219748 | 0.81 | CALCRL (0.80) | CALCRL | |
| SCHEMBL2527617 | 0.81 | CALCRL (0.81) | CALCRLKCNH2 | |
| SCHEMBL2527612 | 0.81 | CALCRL (0.81) | CALCRLKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802637-B1 | CGRP RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2008-10-15 | — | — | EP | disclosed |