Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 3/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755278 | 0.90 | MEN1 (0.54) | MEN1KMT2AABCB1MAPTCYP1A2 | |
| SCHEMBL4753624 | 0.88 | KMT2A (0.72) | MEN1KMT2AABCB1MAPTCYP1A2 | |
| SCHEMBL4755315 | 0.86 | MEN1 (0.53) | MEN1KMT2AABCB1MAPTCYP1A2 | |
| SCHEMBL4090729 | 0.86 | ABCB1 (0.52) | MEN1KMT2AABCB1MAPTCYP1A2 | |
| SCHEMBL4090368 | 0.83 | MEN1 (0.53) | MEN1KMT2AABCB1MAPTCYP1A2 | |
| SCHEMBL4753636 | 0.83 | KMT2A (0.55) | MEN1KMT2AABCB1MAPTCYP1A2 | |
| SCHEMBL4092273 | 0.81 | KMT2A (0.53) | MEN1KMT2AABCB1MAPTCYP1A2 | |
| SCHEMBL4095317 | 0.81 | KMT2A (0.54) | MEN1KMT2AABCB1MAPTCYP1A2 | |
| SCHEMBL4089674 | 0.81 | ABCB1 (0.49) | MEN1KMT2AABCB1MAPTCYP1A2 | |
| SCHEMBL4085117 | 0.81 | KMT2A (0.48) | MEN1KMT2AABCB1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |