Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TACR3 | P29371 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL739486 | 0.81 | TSHR (0.66) | TSHRALDH1A1TDP1POLBNPSR1 | |
| SCHEMBL14296911 | 0.80 | TSHR (0.62) | TSHRALDH1A1TDP1POLBNPSR1 | |
| SCHEMBL12310311 | 0.78 | TSHR (0.62) | TSHRALDH1A1TDP1POLBNPSR1 | |
| SCHEMBL12310314 | 0.78 | TSHR (0.62) | TSHRALDH1A1TDP1POLBNPSR1 | |
| SCHEMBL13573035 | 0.78 | TSHR (0.62) | TSHRALDH1A1TDP1POLBNPSR1 | |
| SCHEMBL6443366 | 0.77 | TSHR (0.58) | TSHRALDH1A1TDP1TACR3NPSR1 | |
| SCHEMBL6443372 | 0.77 | TSHR (0.58) | TSHRALDH1A1TDP1TACR3NPSR1 | |
| SCHEMBL6443369 | 0.77 | TSHR (0.58) | TSHRALDH1A1TDP1TACR3NPSR1 | |
| SCHEMBL166433 | 0.77 | TDP1 (0.58) | TSHRALDH1A1TDP1POLBLMNA | |
| Trifluoroacetic Acid SCHEMBL4755590 | 0.76 | TSHR (0.51) | TSHRALDH1A1TDP1TACR3NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317944-A | Acyclic lipids and methods of use thereof | 雷纳嘉德医疗管理公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118234707-A | Cyclic lipids and methods of use thereof | 雷纳嘉德医疗管理公司 | 2024-06-21 | — | — | CN | disclosed |
| WO-2008155141-A2 | NOVEL FACULTATIVE CATONIC STEROLS | NOVOSOM AG (DE) | 2008-12-24 | — | — | WO | disclosed |