Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.47 |
| ▸ | PPARA | Q07869 | 14/20 | 0.47 |
| ▸ | PPARG | P37231 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888373 | 0.91 | PPARD (0.45) | PPARDPPARAPPARGMAPTKDM4E | |
| SCHEMBL4813287 | 0.91 | PPARD (0.56) | PPARDPPARAPPARGMAPTFFAR1 | |
| SCHEMBL12732457 | 0.88 | PPARD (0.55) | PPARDPPARAPPARGMAPTFFAR1 | |
| SCHEMBL12732456 | 0.87 | PPARD (0.51) | PPARDPPARAPPARGMAPTKDM4E | |
| SCHEMBL2466101 | 0.87 | PPARD (0.51) | PPARDPPARAPPARGMAPTFFAR1 | |
| SCHEMBL24658600 | 0.87 | PPARD (0.51) | PPARDPPARAPPARGMAPTKDM4E | |
| SCHEMBL30003772 | 0.87 | PPARD (0.51) | PPARDPPARAPPARGMAPTKDM4E | |
| SCHEMBL2465202 | 0.86 | PPARD (0.63) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL2463148 | 0.86 | PPARA (0.59) | PPARDPPARAPPARG | |
| SCHEMBL30002979 | 0.86 | PPARD (0.47) | PPARDPPARAPPARGMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1279689-B1 | Mono-, Oligo and Poly-3-(1,1-difluoroalkyl)thiophenes and their use as charge transport materials | MERCK PATENT GMBH (DE) | 2008-10-01 | — | — | EP | disclosed |
| EP-1279689-A3 | Mono-, Oligo and Poly-3-(1,1-difluoroalkyl)thiophenes and their use as charge transport materials | MERCK PATENT GmbH (DE) | 2003-06-04 | — | — | EP | disclosed |
| EP-1279689-A2 | Mono-, Oligo and Poly-3-(1,1-difluoroalkyl)thiophenes and their use as charge transport materials | MERCK PATENT GmbH (DE) | 2003-01-29 | — | — | EP | disclosed |