Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19625984 | 0.79 | — | — | |
| SCHEMBL28166842 | 0.75 | — | — | |
| SCHEMBL28304546 | 0.73 | ABAT (0.31) | NOTUM | |
| SCHEMBL10769457 | 0.72 | TSHR (0.32) | — | |
| SCHEMBL28744254 | 0.72 | POLB (0.32) | — | |
| SCHEMBL3040549 | 0.71 | — | — | |
| SCHEMBL29217592 | 0.71 | — | — | |
| SCHEMBL890924 | 0.66 | — | — | |
| SCHEMBL7434280 | 0.64 | — | — | |
| SCHEMBL28427720 | 0.64 | TSHR (0.42) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038880-B1 | Androstanes and pregnanes for allosteric modulation of GABA receptor | EURO CELTIQUE SA (LU) | 2007-10-17 | — | — | EP | claimed |
| EP-0837874-B1 | NEUROACTIVE STEROIDS OF THE ANDROSTANE AND PREGNANE SERIES | EURO CELTIQUE SA (LU) | 2004-12-15 | — | — | EP | claimed |
| EP-0752860-B1 | ANDROSTANES AND PREGNANES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR | EURO CELTIQUE SA (LU) | 2000-08-23 | — | — | EP | claimed |
| EP-0554436-B1 | GABA RECEPTOR MODULATORS | EURO CELTIQUE SA (LU) | 2000-07-05 | — | — | EP | claimed |
| EP-0335545-B2 | Pharmaceutical formulations for parenteral use | UNIV FLORIDA (US) | 1998-09-23 | — | — | EP | claimed |
| EP-0327766-B1 | Redox systems for brain-targeted drug delivery | UNIV FLORIDA (US) | 1998-04-08 | — | — | EP | claimed |
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | claimed |
| EP-0325187-A1 | 4-alkyl-1, 4-dihydropyridines with PAF-antagonist activity | ALTER, S.A. (ES) | 1989-07-26 | — | — | EP | claimed |
| CN-119192266-A | 3, 3-Disubstituted 19-norpregnane compounds, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-111217811-B | Fused tricyclic compounds and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-113234114-A | 3, 3-disubstituted 19-norpregnane compounds, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-112996510-A | Treatment of chronic traumatic encephalopathy | 克泰克有限责任公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-108976272-B | 3, 3-disubstituted 19-norpregnane compounds, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2021-05-25 | — | — | CN | disclosed |
| EP-3820471-A1 | TREATMENT OF CHRONIC TRAUMATIC ENCEPHALOPATHY | CTEC LLC (US) | 2021-05-19 | — | — | EP | disclosed |
| EP-0500610-A1 | NUCLEOSIDE DERIVATIVES | NYCOMED IMAGING AS (NO) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992004038-A1 | PRO-DRUGS FOR CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |
| WO-1991006554-A1 | NUCLEOSIDE DERIVATIVES | NYCOMED AS (NO) | 1991-05-16 | — | — | WO | disclosed |
| US-4880816-A | Brain-specific delivery of dopamine utilizing dihydropyridine/pyridinium salt-type redox carriers | UNIVERSITY OF FLORIDA (US) | 1989-11-14 | — | — | US | disclosed |
| US-4727079-A | Brain-specific dopaminergic activity involving dihydropyridine carboxamides, dihydroquinoline and isoquinoline carboxamides | UNIVERSITY OF FLORIDA (US) | 1988-02-23 | — | — | US | disclosed |
| US-4622218-A | Testicular-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1986-11-11 | — | — | US | disclosed |