Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 13/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 11/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754668 | 1.00 | DPP4 (0.48) | DPP4DPP8DPP7DPP9KDM4E | |
| SCHEMBL495544 | 1.00 | DPP4 (0.48) | DPP4DPP8DPP7DPP9KDM4E | |
| Hydrochloric Acid SCHEMBL496687 | 0.99 | DPP4 (0.47) | DPP4DPP8DPP7DPP9KDM4E | |
| SCHEMBL496566 | 0.81 | PRMT5 (0.51) | KDM4E | |
| Hydrochloric Acid SCHEMBL496305 | 0.80 | PRMT5 (0.50) | KDM4ESMN1; SMN2 | |
| SCHEMBL495892 | 0.72 | DPP4 (0.45) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL495890 | 0.72 | DPP4 (0.45) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL496004 | 0.72 | DPP4 (0.44) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL496003 | 0.72 | DPP4 (0.44) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL6796135 | 0.71 | KDM4E (0.71) | DPP4DPP8DPP7DPP9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910317-A1 | 1-AMINO LINKED COMPOUNDS | Eli Lilly and Company (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007015805-A1 | 1-AMINO LINKED COMPOUNDS | ELI LILLY AND COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |