⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858618 | 0.85 | — | — | |
| SCHEMBL27984326 | 0.78 | CA1 (0.36) | — | |
| SCHEMBL1605180 | 0.78 | — | — | |
| SCHEMBL292181 | 0.78 | — | — | |
| SCHEMBL16667714 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL28223760 | 0.76 | — | — | |
| SCHEMBL21811906 | 0.76 | — | — | |
| SCHEMBL2522581 | 0.76 | — | — | |
| SCHEMBL364330 | 0.76 | — | — | |
| SCHEMBL9229355 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118369325-A | Therapeutic compounds for HIV virus infection | 吉利德科学公司 | 2024-07-19 | — | — | CN | disclosed |
| WO-2008151927-A2 | 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS | NYCOMED GMBH (DE) | 2008-12-18 | — | — | WO | disclosed |
| US-6815455-B1 | ANTIFOAM AGENTS OF MACROPHAGES; PREVENTING ARTERIOSCLEROSIS | FUJI PHOTO FILM CO., LTD. (JP) | 2004-11-09 | — | — | US | disclosed |
| EP-1197487-B1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2004-01-14 | — | — | EP | disclosed |
| EP-0991644-B1 | BENZO(5,6)CYCLOHEPTAPYRIDINE CYCLIC UREAS AND LACTAMS USEFUL AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORP (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-1197487-A1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | Fuji Photo Film Co., Ltd. (JP) | 2002-04-17 | — | — | EP | disclosed |
| CN-1267297-A | Benzo (5.6) cycloheptopyridine cyclic ureas and lactams as farnesyl protein transferase inhibitors | SCHERING CORP (US) | 2000-09-20 | — | — | CN | disclosed |
| EP-0991644-A1 | BENZO(5,6)CYCLOHEPTAPYRIDINE CYCLIC UREAS AND LACTAMS USEFUL AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORPORATION (US) | 2000-04-12 | — | — | EP | disclosed |
| US-6039683-A | Benzo(5,6)cycloheptapyridine cyclic ureas and lactams useful as farnesyl protein transferase inhibitors | SCHERING CORPORATION (US) | 2000-03-21 | — | — | US | disclosed |
| WO-1998057963-A1 | BENZO(5,6)CYCLOHEPTAPYRIDINE CYCLIC UREAS AND LACTAMS USEFUL AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORPORATION (US) | 1998-12-23 | — | — | WO | disclosed |
| US-5852034-A | Benzo(5,6)cycloheptapyridine cyclic ureas and lactams useful as farnesyl protein transferase inhibitors | SCHERING CORPORATION (US) | 1998-12-22 | — | — | US | disclosed |
| US-5563151-A | PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANALGESICS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0623116-A1 | AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014072-A1 | AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |