Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13983563 | 0.97 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL4755593 | 0.94 | CYP3A4 (0.58) | CYP3A4CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL13983208 | 0.91 | CYP3A4 (0.54) | CYP3A4CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL13983207 | 0.88 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL13983210 | 0.87 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL13983541 | 0.80 | CYP3A4 (0.56) | CYP3A4CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL13983526 | 0.78 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL4632260 | 0.76 | CYP3A4 (0.65) | CYP3A4CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL4754941 | 0.75 | CYP3A4 (0.70) | CYP3A4CYP2C9CYP2C19CYP2D6CYP1A2 | |
| SCHEMBL5902873 | 0.75 | CYP3A4 (0.57) | CYP3A4CYP2C9CYP2C19CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151927-A2 | 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS | NYCOMED GMBH (DE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008151927-A2 | 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS | NYCOMED GMBH (DE) | 2008-12-18 | — | — | WO | disclosed |