Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | TP53 | P04637 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754239 | 0.92 | MAPT (0.41) | MAPTTP53LMNAPPARGPPARD | |
| SCHEMBL1765935 | 0.84 | PPARD (0.46) | MAPTTP53LMNAPPARGPPARD | |
| SCHEMBL1765940 | 0.84 | PTGDR2 (0.42) | MAPTPPARGPPARDPPARAPTGDR2 | |
| SCHEMBL12732419 | 0.84 | MAPT (0.40) | MAPTTP53LMNAPPARGPPARD | |
| SCHEMBL30003978 | 0.84 | MAPT (0.41) | MAPTTP53LMNAPPARGPPARD | |
| SCHEMBL24658530 | 0.84 | MAPT (0.41) | MAPTTP53LMNAPPARGPPARD | |
| SCHEMBL2460952 | 0.83 | PPARD (0.45) | MAPTTP53LMNAPPARGPPARD | |
| SCHEMBL2460958 | 0.83 | PTGDR2 (0.40) | MAPTTP53LMNAPPARGPPARD | |
| SCHEMBL2460955 | 0.83 | PPARD (0.38) | MAPTTP53LMNAPPARGPPARD | |
| SCHEMBL4809536 | 0.82 | PPARD (0.37) | MAPTTP53LMNAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |