Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL16690048 | 0.95 | CDK5 (0.32) | CDK5CDK5R1TDP2NSD2ABL1 | |
| SCHEMBL10424197 | 0.95 | CDK5 (0.32) | CDK5CDK5R1TDP2NSD2ABL1 | |
| Magnesium SCHEMBL4758460 | 0.95 | CDK5 (0.32) | CDK5CDK5R1TDP2NSD2ABL1 | |
| SCHEMBL16414980 | 0.95 | CDK5 (0.32) | CDK5CDK5R1TDP2NSD2ABL1 | |
| Hydrochloric Acid SCHEMBL16689956 | 0.95 | CDK5 (0.32) | CDK5CDK5R1TDP2NSD2ABL1 | |
| Calcium SCHEMBL4758095 | 0.95 | CDK5 (0.32) | CDK5CDK5R1TDP2NSD2ABL1 | |
| Iodide SCHEMBL31265635 | 0.95 | CDK5 (0.32) | CDK5CDK5R1TDP2NSD2ABL1 | |
| Strontium SCHEMBL4758126 | 0.95 | CDK5 (0.32) | CDK5CDK5R1TDP2NSD2ABL1 | |
| SCHEMBL4755246 | 0.95 | CDK5 (0.32) | CDK5CDK5R1TDP2NSD2ABL1 | |
| SCHEMBL31619129 | 0.95 | CDK5 (0.32) | CDK5CDK5R1TDP2NSD2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962499-B2 | Direct preparation of pigmentary pyrrolo-(3,4-C)pyrroles | CIBA SC HOLDING AG (CH) | 2008-03-05 | — | — | EP | disclosed |
| EP-0962499-B1 | Direct preparation of pigmentary pyrrolo-(3,4-C)pyrroles | CIBA SC HOLDING AG (CH) | 2003-03-05 | — | — | EP | disclosed |
| US-6361594-B1 | ONE-STEP PROCESS USING CRYSTAL GROWTH INHIBITORS DURING SYNTHESIS; NO SIZE REDUCTION NEEDED; HIGH DISPERSABILITY, TINCTORIAL STRENGTH, PURITY, AND MIGRATION, HEAT, LIGHT AND WEATHERING FASTNESS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-03-26 | — | — | US | disclosed |
| US-6057449-A | HEATING A DISUCCINATE WITH A NITRILE IN THE PRESENCE OF BASE | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0962499-A2 | Direct preparation of pigmentary pyrrolo-(3,4-C)pyrroles | Ciba SC Holding AG (CH) | 1999-12-08 | — | — | EP | disclosed |
| US-4992101-A | Process for the preparation of opaque diketopyrrolo-pyrrole pigments | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |