⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1151644 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL6564157 | 0.65 | — | — | |
| SCHEMBL9636855 | 0.65 | — | — | |
| SCHEMBL10084677 | 0.65 | — | — | |
| SCHEMBL1752334 | 0.61 | — | — | |
| SCHEMBL4431444 | 0.61 | — | — | |
| SCHEMBL13617914 | 0.61 | — | — | |
| SCHEMBL6310945 | 0.59 | — | — | |
| SCHEMBL8912801 | 0.56 | — | — | |
| SCHEMBL15645149 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633348-B1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARM INC (US) | 2008-10-08 | — | — | EP | claimed |