SCHEMBL4755586

SCHEMBL4755586

Oc1ccnc(-c2ncccc2-c2ccccn2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.48
KDM4E B2RXH2 6/20 0.42
LMNA P02545 3/20 0.42
CCR1 P32246 2/20 0.42
CCR5 P51681 2/20 0.42
CCR8 P51685 2/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
METAP1 P53582 1/20 0.42
BLM P54132 1/20 0.42
HIF1A Q16665 1/20 0.42
DOHH Q9BU89 1/20 0.42
P4HTM Q9NXG6 1/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 2/20 0.41
CASP6 P55212 1/20 0.40
CBFB Q13951 1/20 0.40
KDM6B O15054 1/20 0.39
KDM4A O75164 1/20 0.39
KDM5C P41229 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28599279 0.83 PTGS1 (0.41) KDM1ALMNANPC1RAB9AHTT
SCHEMBL30031 0.82 KDM4E (0.56) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7553180 0.80 CCR1 (0.51) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4844394 0.80 CCR1 (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL2138825 0.80 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL933820 0.80 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL9014126 0.80 KDM4E (0.61) KDM1AKDM4ELMNACCR1CCR5
Dipyridyl SCHEMBL9014332 0.80 KDM4E (0.61) KDM1AKDM4ELMNACCR1CCR5
SCHEMBL16241819 0.80 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL78140 0.80 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009000685-A1 USE OF METAL COMPLEX OXIDATION CATALYSTS TOGETHER WITH ZINC COMPOUNDS IN LAUNDRY COMPOSITIONS BASF SE (CH) 2008-12-31 WO disclosed
WO-2007128745-A1 USE OF METAL COMPLEX OXIDATION CATALYSTS TOGETHER WITH MAGNESIUM COMPOUNDS IN LAUNDRY COMPOSITIONS CIBA HOLDING INC. (CH) 2007-11-15 WO disclosed
US-20070135323-A1 Use of metal complex compounds as oxidation catalysts RECKITT BENCKISER N.V. (NL) 2007-06-14 US disclosed
CN-1934144-A Grafting of transition metal complexes on supports. TOTAL PETROCHEMICALS RES FELUY (BE) 2007-03-21 CN disclosed
US-20070032629-A1 Grafting of transition metal complexes on supports BANET PHILLIPE 2007-02-08 US disclosed
EP-1718684-A1 GRAFTING OF TRANSITION METAL COMPLEXES ON SUPPORTS. TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2006-11-08 EP disclosed
EP-1694807-A1 USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS Reckitt Benckiser N.V. (NL) 2006-08-30 EP disclosed
WO-2005075522-A1 GRAFTING OF TRANSITION METAL COMPLEXES ON SUPPORTS. TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-08-18 WO disclosed
EP-1559728-A1 Grafting of transition metal complexes on supports TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-08-03 EP disclosed
EP-1556468-A1 USE OF METAL COMPLEX COMPOUNDS AS CATALYSTS FOR OXIDATION USING MOLECULAR OXYGEN OR AIR Ciba SC Holding AG (CH) 2005-07-27 EP disclosed
WO-2005061688-A1 USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS RECKITT BENCKISER N.V. (NL) 2005-07-07 WO disclosed
EP-1521820-A1 USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS Ciba SC Holding AG (CH) 2005-04-13 EP disclosed
WO-2004039933-A1 USE OF METAL COMPLEX COMPOUNDS AS CATALYSTS FOR OXIDATION USING MOLECULAR OXYGEN OR AIR CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-05-13 WO disclosed
EP-1383857-A2 USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS Ciba SC Holding AG (CH) 2004-01-28 EP disclosed
WO-2004007657-A1 USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-01-22 WO disclosed
WO-2002088289-A2 USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-11-07 WO disclosed