Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 16/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18398749 | 0.83 | KDM4C (0.44) | SLC22A12KDM4CTDP1KDM4EMEN1 | |
| SCHEMBL18776110 | 0.82 | SLC22A12 (0.42) | SLC22A12TDP1 | |
| SCHEMBL3074800 | 0.80 | KDM4C (0.49) | SLC22A12KDM4CTDP1KDM4EMEN1 | |
| SCHEMBL1656950 | 0.80 | POLB (0.52) | SLC22A12KDM4CTDP1KDM4EMEN1 | |
| SCHEMBL11504517 | 0.78 | KDM4C (0.50) | SLC22A12KDM4CTDP1KDM4EMEN1 | |
| SCHEMBL30425929 | 0.77 | KDM4C (0.46) | SLC22A12KDM4CTDP1KDM4EMEN1 | |
| SCHEMBL20511499 | 0.77 | KDM4C (0.46) | SLC22A12KDM4CTDP1KDM4EMEN1 | |
| SCHEMBL16611699 | 0.76 | HSD17B10 (0.49) | SLC22A12KDM4CTDP1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL16612069 | 0.75 | HSD17B10 (0.48) | SLC22A12KDM4CTDP1KDM4EMEN1 | |
| SCHEMBL10447747 | 0.74 | POLB (0.61) | TDP1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896048-A2 | PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE (PACAP) RECEPTOR (VPAC2) AGONISTS AND THEIR PHARMACOLOGICAL METHODS OF USE | Bayer Pharmaceuticals Corporation (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006121588-A2 | PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE (PACAP) RECEPTOR (VPAC2) AGONISTS AND THEIR PHARMACOLOGICAL METHODS OF USE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-11-16 | — | — | WO | disclosed |