⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121239 | 0.63 | — | — | |
| SCHEMBL30728052 | 0.56 | — | — | |
| SCHEMBL29546936 | 0.54 | — | — | |
| SCHEMBL5619234 | 0.53 | — | — | |
| SCHEMBL32683621 | 0.52 | — | — | |
| SCHEMBL7408468 | 0.50 | — | — | |
| SCHEMBL7962744 | 0.49 | — | — | |
| SCHEMBL27882713 | 0.48 | — | — | |
| SCHEMBL2045014 | 0.48 | — | — | |
| SCHEMBL6643717 | 0.47 | CYP19A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621225-A | Imidazopyridoindole compound and preparation method and application thereof | 石河子大学 | 2022-06-14 | — | — | CN | claimed |
| EP-0018857-B1 | PYRIMIDO AND IMIDAZO-PYRIDO-INDOLE-DIONES, THEIR PREPARATION AND THERAPEUTIC USE | SYNTHELABO (FR) | 1983-01-19 | — | — | EP | claimed |
| EP-0018857-A1 | Pyrimido and imidazo-pyrido-indole-diones, their preparation and therapeutic use | SYNTHELABO (FR) | 1980-11-12 | — | — | EP | claimed |
| CN-114621225-A | Imidazopyridoindole compound and preparation method and application thereof | 石河子大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621225-A | Imidazopyridoindole compound and preparation method and application thereof | 石河子大学 | 2022-06-14 | — | — | CN | disclosed |
| EP-1390367-B1 | DIHYDROIMIDAZO 5,1-A -$G(b)-CARBOLINE DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINE | MACEF (FR) | 2008-07-09 | — | — | EP | disclosed |
| US-20080096909-A1 | APOMORPHINE INHIBITORS OF AMYLOID-BETA (ABETA) FIBRIL FORMATION AND THEIR USE IN AMYLOIDOSIS BASED DISEASE | CYTOKINE PHARMASCIENCES, INC. (US) | 2008-04-24 | — | — | US | disclosed |
| US-7291627-B2 | Dihydroimidazo[5.1-a]-beta-carboline derivatives, method for their preparation, and their application as a drug | MACEF (FR) | 2007-11-06 | — | — | US | disclosed |
| US-20060089372-A1 | Dihydroimidazo[5,1-a]sg(b)-carboline derivatives, method for preparing same and use thereof as medicine | MACEF (FR) | 2006-04-27 | — | — | US | disclosed |
| EP-1390367-A1 | DIHYDROIMIDAZO 5,1-A]-$G(b)-CARBOLINE DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINE | MACEF (FR) | 2004-02-25 | — | — | EP | disclosed |
| US-20030187011-A1 | Apomorphine inhibitors of amyloid-beta (Abeta) fibril formation and their use in amyloidosis based disease | CYTOKINE PHARMASCIENCES, INC. | 2003-10-02 | — | — | US | disclosed |
| WO-2003053356-A2 | APOMORPHINE INHIBITORS OF AMYLOID-β (Aβ) FIBRIL FORMATION AND THEIR USE IN AMYLOIDOSIS BASED DISEASE | CYTOKINE PHARMASCIENCES, INC. (US) | 2003-07-03 | — | — | WO | disclosed |
| WO-2002092598-A1 | DIHYDROIMIDAZO [5,1-A]-$G(b)-CARBOLINE DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINE | MACEF (FR) | 2002-11-21 | — | — | WO | disclosed |
| US-4358451-A | ANOXIA, PSYCHOTROPIC | SYNTHELABO (FR) | 1982-11-09 | — | — | US | disclosed |
| US-4358451-A | ANOXIA, PSYCHOTROPIC | SYNTHELABO (FR) | 1982-11-09 | — | — | US | disclosed |
| US-4358451-A | ANOXIA, PSYCHOTROPIC | SYNTHELABO (FR) | 1982-11-09 | — | — | US | disclosed |
| EP-0018857-A1 | Pyrimido and imidazo-pyrido-indole-diones, their preparation and therapeutic use | SYNTHELABO (FR) | 1980-11-12 | — | — | EP | disclosed |