Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755281 | 0.86 | CYP2C9 (0.46) | CYP2C9CYP3A4LMNACYP2D6MAPK1 | |
| SCHEMBL16758698 | 0.86 | CYP2C9 (0.43) | CYP2C9CYP3A4LMNACYP2D6MAPK1 | |
| SCHEMBL16908428 | 0.84 | CYP2C9 (0.45) | CYP2C9CYP3A4LMNACYP2D6MAPK1 | |
| SCHEMBL18954292 | 0.84 | CYP2C9 (0.56) | CYP2C9CYP3A4LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL11556453 | 0.82 | CYP2C9 (0.52) | CYP2C9L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL4078041 | 0.82 | CYP2C9 (0.38) | CYP2C9CYP3A4LMNACYP2D6MAPK1 | |
| SCHEMBL8444430 | 0.81 | CYP2C9 (0.51) | CYP2C9CYP3A4LMNAL3MBTL1ALDH1A1 | |
| Sulfuric Acid SCHEMBL2527707 | 0.80 | CDC25A (0.37) | CYP2C9L3MBTL1USP2 | |
| SCHEMBL28949348 | 0.79 | CYP2C9 (0.47) | CYP2C9CYP3A4LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL29903842 | 0.78 | CYP2C9 (0.45) | CYP2C9CYP3A4LMNACYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1134268-B1 | Antistatic composition | KAO CORP (JP) | 2008-03-12 | — | — | EP | disclosed |
| US-6620231-B2 | Mixture with polarity solvents; protective devices | KAO CORPORATION (JP) | 2003-09-16 | — | — | US | disclosed |
| EP-1134268-A1 | Antistatic composition | KAO CORPORATION (JP) | 2001-09-19 | — | — | EP | disclosed |