Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754035 | 1.00 | TSHR (0.43) | TSHRALDH1A1TDP1MAPTLOX | |
| SCHEMBL4754670 | 1.00 | TSHR (0.43) | TSHRALDH1A1TDP1MAPTLOX | |
| SCHEMBL547962 | 1.00 | TSHR (0.43) | TSHRALDH1A1TDP1MAPTLOX | |
| SCHEMBL4756743 | 1.00 | TSHR (0.43) | TSHRALDH1A1TDP1MAPTLOX | |
| SCHEMBL4756519 | 1.00 | TSHR (0.43) | TSHRALDH1A1TDP1MAPTLOX | |
| SCHEMBL7616059 | 1.00 | TSHR (0.43) | TSHRALDH1A1TDP1MAPTLOX | |
| SCHEMBL4754566 | 1.00 | TSHR (0.43) | TSHRALDH1A1TDP1MAPTLOX | |
| SCHEMBL4755738 | 1.00 | TSHR (0.43) | TSHRALDH1A1TDP1MAPTLOX | |
| SCHEMBL4757182 | 1.00 | TSHR (0.43) | TSHRALDH1A1TDP1MAPTLOX | |
| SCHEMBL1228368 | 1.00 | TSHR (0.43) | TSHRALDH1A1TDP1MAPTLOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110612-A2 | NOVEL COMPOUNDS AND LUBRICATING COMPOSITIONS COMPRISING THE SAME | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2008-09-18 | — | — | WO | disclosed |