Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.57 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707472 | 0.88 | KCNH2 (0.55) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL13264493 | 0.85 | KCNH2 (0.55) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL920361 | 0.83 | KCNH2 (0.62) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL707415 | 0.83 | KCNH2 (0.61) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL2798199 | 0.82 | KCNH2 (0.60) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL9985880 | 0.81 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL4789860 | 0.81 | KCNH2 (0.66) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL2800075 | 0.81 | KCNH2 (0.51) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL5036915 | 0.80 | KCNH2 (0.61) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL2795099 | 0.80 | KCNH2 (0.51) | KCNH2KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001126-A1 | SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBATERIAL AGENTS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |