Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30134003 | 0.84 | KDM4E (0.44) | KDM4ETSHRALOX15KMT2AMEN1 | |
| SCHEMBL102595 | 0.84 | KDM4E (0.44) | KDM4ETSHRALOX15KMT2AMEN1 | |
| SCHEMBL25139836 | 0.80 | PTGS1 (0.40) | KDM4ETSHRTDP1KMT2AMEN1 | |
| SCHEMBL22234994 | 0.76 | PLA2G10 (0.43) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL30428448 | 0.76 | PLA2G10 (0.46) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL29276421 | 0.76 | PLA2G10 (0.46) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL2431316 | 0.74 | PTGS1 (0.43) | KDM4ETSHRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25528035 | 0.74 | GRM1 (0.42) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL19859465 | 0.73 | GRM5 (0.50) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL15003281 | 0.72 | KDM4E (0.36) | KDM4ETSHRALOX15PLA2G10ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001126-A1 | SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBATERIAL AGENTS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |