Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4705477 | 1.00 | F10 (0.53) | F10F2KLKB1PLAT | |
| SCHEMBL4758892 | 0.86 | F10 (0.53) | F10F2KLKB1PLAT | |
| SCHEMBL4705527 | 0.86 | F10 (0.53) | F10F2KLKB1PLAT | |
| SCHEMBL4702691 | 0.86 | F10 (0.53) | F10F2KLKB1PLAT | |
| SCHEMBL4704105 | 0.85 | F10 (0.53) | F10F2KLKB1PLAT | |
| SCHEMBL4704284 | 0.85 | F10 (0.57) | F10F2KLKB1PLAT | |
| SCHEMBL4704286 | 0.85 | F10 (0.57) | F10F2KLKB1PLAT | |
| SCHEMBL4756206 | 0.84 | F10 (0.51) | F10F2KLKB1PLAT | |
| SCHEMBL4704241 | 0.82 | F10 (0.56) | F10F2KLKB1 | |
| SCHEMBL4701981 | 0.80 | F10 (0.51) | F10F2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567489-B1 | PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF THROMBIN AND FACTOR XA | GLAXO GROUP LTD (GB) | 2008-07-23 | — | — | EP | disclosed |