Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14699582 | 1.00 | NPSR1 (0.38) | NPSR1KMT2APOLBEPHX2SMN1; SMN2 | |
| SCHEMBL1342010 | 0.86 | — | — | |
| SCHEMBL3827173 | 0.80 | BTK (0.47) | KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL3827171 | 0.80 | BTK (0.47) | KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL1340685 | 0.78 | SMN1; SMN2 (0.50) | KMT2ASMN1; SMN2HSD17B10NAAACYP3A4 | |
| SCHEMBL1341778 | 0.78 | SMN1; SMN2 (0.55) | NPSR1KMT2AEPHX2SMN1; SMN2HSD17B10 | |
| SCHEMBL23573526 | 0.78 | EPHX1 (0.49) | KMT2APOLBHSD17B10NAAA | |
| SCHEMBL23573362 | 0.78 | EPHX1 (0.49) | KMT2APOLBHSD17B10NAAA | |
| SCHEMBL23573363 | 0.78 | EPHX1 (0.49) | KMT2APOLBHSD17B10NAAA | |
| SCHEMBL16336089 | 0.77 | POLB (0.40) | NPSR1POLBSMN1; SMN2HSD17B10MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888574-A2 | NEW ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006126171-A2 | NEW ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2006-11-30 | — | — | WO | disclosed |