SCHEMBL475967

SCHEMBL475967

C=C(O)O[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16874331 0.70
SCHEMBL8595883 0.70
SCHEMBL1041226 0.67
SCHEMBL4532239 0.65
SCHEMBL15821667 0.65
Ethylene SCHEMBL10880749 0.65
SCHEMBL21295311 0.64
SCHEMBL9219479 0.63
SCHEMBL9705842 0.63
SCHEMBL4767831 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11884820-B2 Silicone gel composition and cured product thereof, and power module SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-30 US claimed
US-11629234-B2 Polymeric polymerization initiator and method for producing polymeric polymerization initiator SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-04-18 US claimed
US-20210317310-A1 SILICONE GEL COMPOSITION AND CURED PRODUCT THEREOF, AND POWER MODULE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-10-14 US claimed
EP-3862367-A1 HIGH-MOLECULAR-WEIGHT POLYMERIZATION INITIATOR AND PRODUCTION METHOD FOR HIGH-MOLECULAR-WEIGHT POLYMERIZATION INITIATOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-08-11 EP claimed
EP-3831887-A1 SILICONE GEL COMPOSITION AND CURED PRODUCT THEREOF, AND POWER MODULE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-06-09 EP claimed
WO-2020070966-A1 (METH)ACRYLIC GRAFT SILICONE AND PRODUCTION METHOD FOR SAME 信越化学工業株式会社 2020-04-09 WO claimed
WO-2020070964-A1 HIGH-MOLECULAR-WEIGHT POLYMERIZATION INITIATOR AND PRODUCTION METHOD FOR HIGH-MOLECULAR-WEIGHT POLYMERIZATION INITIATOR 信越化学工業株式会社 2020-04-09 WO claimed
WO-2020026760-A1 SILICONE GEL COMPOSITION AND CURED PRODUCT THEREOF, AND POWER MODULE 信越化学工業株式会社 2020-02-06 WO claimed
EP-2190849-B1 4-(9-(3,3-DIFLUOROCYCLOPENTYL)-5,7,7-TRIMETHYL-6-OXO-6,7,8,9-TETRAHYDRO-5H-PYRIMIDO[4,5-B[1,4]DIAZEPIN-2-YLAMINO)-3-METHOXYBENZAMIDE DERIVATIVES AS INHIBITORS OF THE HUMAN PROTEIN KINASES PLK1 TO PLK4 FOR THE TREATMENT OF PROLIFERATIVE DISEASES VERTEX PHARMA (US) 2013-11-20 EP claimed
US-8461149-B2 Compounds useful as protein kinase inhibitors VERTEX PHARMACEUTICALS INCORPORATED (US) 2013-06-11 US claimed
US-20110263575-A1 Compounds Useful as Protein Kinase Inhibitors VERTEX PHARMACEUTICALS INCORPORATED 2011-10-27 US claimed
US-20110034613-A1 TWO-PART ORGANOPOLYSILOXANE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-02-10 US claimed
EP-2190849-A2 COMPOUNDS USEFUL AS PROTEIN KINASES INHIBITORS Vertex Pharmceuticals Incorporated (US) 2010-06-02 EP claimed
WO-2009023269-A2 4-(9-(3, 3-DIFLUOROCYCLOPENTYL) -5, 7, 7-TRIMETHYL-6-OXO-6, 7, 8, 9-TETRAHYDRO-5H-PYRIMIDO [4, 5-B[1, 4] DIAZEPIN-2-YLAMINO)-3-METHOXYBENZAMIDE DERIVATIVES AS INHIBITORS OF THE HUMAN PROTEIN KINASES PLK1 TO PLK4 FOR THE TREATMENT OF PROLIFERATIVE DISEASES VERTEX PHARMACEUTICALS INCORPORATED (US) 2009-02-19 WO claimed
EP-1063227-B1 HYDRAZIDE FIXED TO RESIN AND DERIVATIVE THEREOF, AND METHOD FOR SYNTHESIZING PYRAZOLONES IN SOLID PHASE JAPAN SCIENCE & TECH AGENCY (JP) 2007-10-31 EP claimed
US-6271391-B1 Hydrazide fixed to a resin and derivatives thereof, and a method for synthesizing pyrazolones in solid phase JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2001-08-07 US claimed
EP-1063227-A1 HYDRAZIDE FIXED TO RESIN AND DERIVATIVE THEREOF, AND METHOD FOR SYNTHESIZING PYRAZOLONES IN SOLID PHASE Japan Science and Technology Corporation (JP) 2000-12-27 EP claimed
US-5064898-A Room temperature-curable organopolysiloxane composition and method for the preparation thereof SHIN-ETSU CHEMICAL CO. (JP) 1991-11-12 US claimed
US-4908451-A Process for preparing α-substituted carbonyl compound AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1990-03-13 US claimed
US-4892936-A Process for the preparation or α-azo esters AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1990-01-09 US claimed