SCHEMBL4759983

SCHEMBL4759983

CCOCC(N)C1CN(c2ccc3c(=O)n(N)c(=O)n(C4CC4)c3c2C)CC1C

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.30
LITAF Q99732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4504705 1.00 TNF (0.30) TNFLITAF
SCHEMBL4525807 1.00 TNF (0.30) TNFLITAF
SCHEMBL4514155 0.91 TNF (0.31) TNFLITAF
SCHEMBL4505623 0.91 TNF (0.31) TNFLITAF
SCHEMBL4503065 0.90 KCNH2 (0.30)
SCHEMBL4518390 0.90 KCNH2 (0.30)
SCHEMBL4514749 0.90 KCNH2 (0.36) TNFLITAF
SCHEMBL1384532 0.90 KCNH2 (0.36) TNFLITAF
SCHEMBL4713150 0.90 KCNH2 (0.36) TNFLITAF
SCHEMBL4759973 0.90 KCNH2 (0.36) TNFLITAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1255739-B1 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS WARNER LAMBERT CO (US) 2008-06-11 EP disclosed